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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '693a288ae55710c133928b32dbc2c5728ab31dea101dbcd5358fac065de79e20' 
  AND token = 'WjMnHULWMS6WwrlVzXx9UR3Y4CBqIf1OUaSMAL+rVkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}