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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380e6c5e2a6a389e1fca4defb9ede5b8ce427c457501a1635f51b3ca96fc468f' 
  AND token = 'jmNj0pioGQOz/A6Iz6q1fTHz8BAfOlu/pKLieBPkZv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}