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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64fe87c75641b1e82572e852c89d957227a84d2ba4dd7ea61cb9798206454543' 
  AND token = '9OB091XnG2vyTgcLYzQKcic+Azwky68ZjNoOoQRT3pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}