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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b01388e418912ed1d6d53a0867c3d9d74652d8ee3af64b6ae0f51209af4d0ab6' 
  AND token = 'pfYCOm/gG6RgAMVWqE10iVvsVbeR0vJ+TSpinNLLXNc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}