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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0c37a31540682d3d18203883e9a9b0d0f8439d2c32eb26ed721f3a02b126373' 
  AND token = 'upTAcLYp8W9RdDn8DDiE8MECXGbXPisk6o9HgIe9Z/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}