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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e374d98f2f9077d55200d1b7f0209d9a7f8e5271181011f78801d8e7022bb7c' 
  AND token = 'xt6wedvUNHL57j7UYH+G5bd1xdqhq/F+gHWug87cxDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}