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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b113f448b7ed2e1e7da086579a63ecfd51f8e49f0adb15b84ec214e6152f4c1' 
  AND token = 'I3jPkIhzKSljTQbZZ1dLCLUi7tMfdEv+X32YslM3K0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}