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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '780e53ab5236d01bed66170a8bb267c3f6d85d3c95efa7ef100dceae8f6bb82b' 
  AND token = 'rZD9nV/1x+E6N6gLjRf3AFkMKj7bjjGAboepEo62RtI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}