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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4eadc7039c7d7b76b65ba57451a9a9797f02be100d643654b4c029a71b8b15' 
  AND token = 'A4f1p4n+0QISXsW/Txm0Ji7hKsH6coVTe8Ya65GLPbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}