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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f8d5f672a7b4697d24d0096b8f518356a354bb2cb32d39eff2d375cbd7f4191' 
  AND token = 'v9/cUh8AokzKULkf9SE+50rNl+Xye0kTbUfhfL9+VKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}