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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75edfc33471637e70d04f5c8c055d3b4b5ee6551cd738840549e8e4bbbc0db3e' 
  AND token = 'FmC7Z2DGdIto4LhT2u+sh3lXbBxzXQVHBkkZqQRE5Ec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}