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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77e78aab2364604d813dfbe3357aba8c2335370a6931b01a8453dc5fc72a14a4' 
  AND token = 'hN8JfP0dhFLKT8na+PP2nCEDeKcBgHXprE/h8zWDTz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}