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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2451077dfa5369831a0ffc3d334bc98e2b781766d7e5a8d52f263b31d442a99' 
  AND token = 'w3UNdb8mzU9Tsdt+D7dhh1lZRgXHfFX9aD9fcu1K6+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}