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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eec96e792267b6d42a86d1ec19a3ed44d08faddfd77e4c0afee1c4cde7c999d' 
  AND token = 'bBNNv3BvQvlZ2c2/v//AiVp1Le/kMyzh8+vjYiq3nUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}