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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c48f1c015254d03ebd7e013c2f2a0d209ae9f440e838eb3e55cfad900438791' 
  AND token = 'GPFadGDn9muOGHE4qJ11dL+QktkuUeOxntf4B8u/0wY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}