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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b78003125f68f82370e2a8c30a25d3c48f77f42aee2fc1b464070fa9096cd303' 
  AND token = 'A/G6ThC/HroK5biJ7M56eeiIvpRZS8/g3+DdZWaaU1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}