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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f38e0cd1270fff3a9482b7df9a53cbff4814ad2a5453db5b51474a71032b1896' 
  AND token = 'hd7b0Rjyv0rr60APc01XkuajfVzWlVLHGMBZJxf2F98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}