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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129a4e8805addd2fa75fceed650cfb4abd2bb82053c6aec45d0aa8fdd9471fa6' 
  AND token = 'WEyd1/TICS7OB/MzN1/PL19MN0mwqRsedf7SBTKwheE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}