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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5245adb5bd84a12ffaae21e1aad3e64256a32db90174e8a7e0aa75744bf385e' 
  AND token = 'B8k7gIpj3th9I968XeHtSz5sdcyB9UdH4DDcOXiO378=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}