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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '112c210247d82f223d7d26955f1a123d0b8ce547ffc12388d9c098f38e049d06' 
  AND token = 'SSaCz/h8mEHdkH9v1Y/uYDuI+x0NR7StbqiJLCHF2ck=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}