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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be6561ddce4d576837d2aa4b102810c0933ea7f64920f1aae4a812a28b1d2464' 
  AND token = 'YSTObEal1WuNriP2KsrtnLq62Sdyxgf4mJ09k4eZb7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}