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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15bfb3edad5c9a0ac4790bf020d715dfa6061cfd1ecd81e94b60d0a4300d2a37' 
  AND token = '+ggS2Dl4/gzE62QVFEyviDmm3pQMt68l0MR4zf6kW0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}