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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81347dd37c3dc1ab46e3f44c3d3b0801d464c611929d861863aa011019dd8402' 
  AND token = '5FAt1uGbXVOWD8QueFQv21EFNLK5bgef5t8JSGy+iWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}