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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '088af25ed1d5df783d66106fbf2061df1f27b2b1be4991772b23f563faf73a88' 
  AND token = 'EAn9Wzkkg4VHA3ca4PXbiqL+44erTwi8QeZf5xWvf6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}