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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a25ae0b1d2011d4aef478d623b9c9133e00ed62d09f3e73c68f2599e556a52b' 
  AND token = 'LJq9Wz3XqlSkpKkDw7OGceaB6CVrxAmyVG7EYleNccw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}