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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e38b4084844336cbf2483e3047c35f6d89d7b5cef674132e04abf4850cfd42' 
  AND token = 'h8FRXgWLATcBGTuRe744sFuMXMUFdC+f761renEeLqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}