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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3e3dd9a5296768f988343ecc7059e209105bcbadc667f25682dbdaf0d2a5603' 
  AND token = 'KFIBv/6LNGf3igMHpCO8MNAn5vTXXJhjWN1KpTrRiag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}