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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2173468ebb92a549484f6351327a7e143d086a0d1c1e022cb7d1ae7a8091771' 
  AND token = 'v4LA3NIG8bQSQIFx2sausCDzyS/TqesCbflyGxe6ceI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}