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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7584211456edbdd05a8538da0a39720bff78506497ca7e6cfc5ba2d7ea1d13' 
  AND token = 'Vra+41CuapDYISm/+cWFH+rFlcHXY3LN26ZFhgO4nA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}