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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de61c60f623c548538d3d53db7ac7fab1f2fa267c24e4c13fbf3399160b73dd1' 
  AND token = 'ySkHQYN/BVjTge/NjejkkyJmhKJ4ke6ROwxSM4dQ6lA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}