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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9c5b6a824d627eecf9d054efbf5d2d87ae7c5afef42232b2501c6640729b308' 
  AND token = 'u+jC8mFTxjK0Ok5lrE/r1jgi/D3+HyUv0XbSZqoLgdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}