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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3fc24c12afc768383eef10d5a618cf2c3bc09ed94744e907c012e8efa446262' 
  AND token = '3n4vAtQn4Ecl/A6WMFj4jKK2phgO5h6U8IMlJwXgwOs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}