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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a0321b5c6fb1ddf07a26d5f5ad7592a98c4c812fb1214d5b16e96c00b375289' 
  AND token = 'RNV4OdR1EKi+toPWl+dLzuLCEiLikvsIDpseK7f/3AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}