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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0a099b12bd026b332821ba4dd138bc70db2fd23b1ca7ec7e0b7230726fa0b2' 
  AND token = 'StiRPeoy8tQO8HW3T4XPOjBr2tYYrVOU1WLZmZCE0hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}