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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fae41f098755c1b8d8f44b7cfe02eb3b9e2b0d363e8cd952288db4e81a8027f9' 
  AND token = 'PmdD+wKycn0HVGpD+2mYYBVe46yPLf6lVhHWm1CwPdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}