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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb7a5db0cfa9ca3b91226a63d0fe4945e104af06be30d09bf4a89dcac2c1579' 
  AND token = '5Alx6zEWTbUD9VdS/n7uiXNCN8+ilD1THMZ5xqyhwp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}