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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0ca7a9c01c67bab1b85bb32447ce223585523d7fc562bf15ce849e19b613466' 
  AND token = 'xxeToMeO6LBKNFkY0d1UMkBeq/m3fL/IoEpPz/yV1zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}