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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b1b4919893727f8cc8068ac8db913c2d0c281c0127d470a8b24caaffa86580' 
  AND token = 'mRwKbdnvIFAdhkClRLScMEyYeIXngly2MxNa+0FwD0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}