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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16d7537ae4de06e1e346473362e1486b096a9356eb072c7e6b0f1f93055a7b8' 
  AND token = 'DMHsg1l274oGsLOPGeMLfuYx3mldt0jEc7JwtCHjWiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}