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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dad3f6499f8ec21fe46d372bcba991842128f31d3b54227dd992365c30999fd' 
  AND token = '3VDTys1Np3AoFCwp6BQYS7vTOiYfpT/QdL+HmM1jDRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}