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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b6379ff5cb49db51d448a6e28f2f84d39081d4550dd509b2edef334e94bf75' 
  AND token = 'ErNt9fcjJ/1AEic9tPNuWZYyjIzR6JvekmhIb4y/OsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}