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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d914af7c1d08b6c704c725aa080a14457e558700f5bafdf78b75646a0097bdc' 
  AND token = 'rTbhf8Dx8/p8c/zPg8MJTNG2yQL7n7sJg0aZE6yRUN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}