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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '680c27bd32e2b2a453e467f377996e62a70e16e87a2746a2824f0a371dd71b0b' 
  AND token = 'no8bdvoQQWuOXeA6O+Oxq/bupMFVj6ES4dtErPmoVag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}