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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1a2b354aef88d497b63e22a8e549cc476f61bafd95af02c49387a7f725ee414' 
  AND token = '183C7aOelWsCCL5hbLsd6ulZsB+a0lW0CfZ7t+5r+XU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}