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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63d1a31fd4c3279790110eb92ff4357f0216637b3c8ed2ce51c7653ae40ee9e' 
  AND token = 'apXM4hHWyVqZfKr9XqLzy+zsmCCn/DsO/ZiW9AeySQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}