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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72954c30b217cc0c7efea16a05de31e2d9e601adf7f213b2eb857ca50ae92386' 
  AND token = 'DJQtdCs+6VJoubLv1xkqxmgsn56slpsemcZ0tV3JcaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}