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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c468731d3b917a3524d4a89df0d60be0a486592737c12ea7b0c6c0ec652aa3' 
  AND token = 'W0cpYe4ZqjL2H8LYG1hrvr0FfeED9gTPRRj0g1RjX0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}