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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3d225ddff2941bc4909b8427321ab00740ef90d8c8f10c5f93bddad26050aed' 
  AND token = 'Dria7W00pgL415V4/plZoAD3nGifTZTQ2TaGtvrJG/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}