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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fd4f5a851e4ff153a32ec98e6c05059442ed70b4070948b41fbfc15a56c859e' 
  AND token = 'pgf9zUxQgicJ+wK3fi7RSyPCN8BtGUECOuB1bYtRuyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}