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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0954e934bcb86da0b1b3effa5c8bf290fab642202a3b8954a672d15b9bbaf02' 
  AND token = 'Zp8F2hERm96VQlW5ZcdeJ2/vfwJxc++rU304hz/Cg9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}